소아 진정시 Chloral Hydrate, Hydroxyzine복용 후 Midazolam의 점막하 투여 용량에 따른 진정효과에 관한 연구
Sedative Effect of Sublingual Midazolam after Oral Chloral Hydrate or Hydroxyzine in Children
이현정, 정상혁, 백광우,
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이현정 ( Lee Hyun-Jung ) - 이화여자대학교 임상치의학대학원 소아치과학교실
정상혁 ( Jung Sang-Hyuk ) - 이화여자대학교 의과대학 예방의학교실
백광우 ( Baek Kwang-Woo ) - 이화여자대학교 임상치의학대학원 소아치과학교실
KMID : 0980220080080010016
Abstract
Recently combining regimen of minimal doses of chloral hydrate, hydroxyzine and midazolam is good in sedation of children. Midazoalm, water soluble benzdiazepine, has rapid onset and relatively short duration of action. And midazolam has prospective amnesic effect. With these advantages midazolam is popular in conscious sedation for children. This study was to reveal the dose-dependency of behavior and physiologic effects of sublingual midazolam. Sedation records were surveyed retrospectively, of which the patients admitted from April, 2005 to July, 2007. we assigned three groups according the dose of midazolam, 0.1 mg/kg, 0.2 mg/kg and 0.3 mg/kg, respectively and the behavioral evaluation was analyzed with Houpt scale statistically. Combined sublingual midazolam increased the success rate in sedation and the vital signs were stable during sedation.
키워드
Conscious sedation;Submucosal midazolam;Chloral hydrate;Hydroxyzine
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